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HPLC ANALYSIS

HPLC ANALYSIS

The Department of Clinical Pathology of the Noguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, is at the forefront of scientific innovation, offering advanced High-Performance Liquid Chromatography (HPLC) analysis for various applications, including plant fingerprinting and pharmacokinetic studies. Our state-of-the-art laboratories are equipped with cutting-edge HPLC systems and staffed by highly-experienced professional scientists, ensuring accurate and reliable results for a range of research and pharmaceutical needs. Details of the HPLC-based services offered at the Department are provided in the following sections.

HPLC plays a pivotal role in the field of plant science by enabling accurate plant fingerprinting, a technique used to identify and quantify the diverse compounds present in plant extracts. Plants contain a vast array of bioactive compounds, including phenolic compounds, alkaloids, flavonoids, and more, each contributing to their potential therapeutic properties. HPLC allows us to separate and identify these compounds based on their unique chemical characteristics, creating a distinct “fingerprint” that can aid in plant species identification, quality control, and the assessment of bioactivity.

Our department employs HPLC-based techniques to analyze plant extracts, contributing to the identification of key compounds and their concentrations. This information is invaluable for researchers studying plant chemistry, herbal medicine, and natural product development, as well as for industries involved in botanicals, dietary supplements, and traditional medicine.

HPLC is an indispensable tool in pharmacokinetic studies, which involve the analysis of how a substance is absorbed, distributed, metabolized, and excreted within a living organism. Our advanced HPLC systems allow for precise quantification of drug compounds and their metabolites in biological samples such as blood, plasma, and urine. By monitoring the concentration-time profiles of these substances, we gain insights into their pharmacokinetic parameters, bioavailability, half-life, and clearance.

Pharmacokinetic studies are crucial in drug development, helping researchers and pharmaceutical companies make informed decisions about dosing regimens, drug interactions, and safety profiles, as well as in the management of disease conditions Our department’s expertise in HPLC analysis ensures accurate pharmacokinetic data, contributing to the advancement of medical research and the optimization of therapeutic interventions.

Whether you’re conducting plant research, drug development, or other related studies, our department offers customized HPLC analysis solutions tailored to your specific needs. We collaborate closely with researchers, scientists, and industry professionals to design and execute analytical protocols that deliver precise results, fostering advancements in various fields.

We prioritize from onset quality management system. Our laboratories are committed to complying with quality assurance protocols. We monitor laboratory examination results rigorously through equipment calibration, internal quality control and external quality control programs. Our Quality Management System is based on ISO 9001 and ISO 15189. Our Institutional Quality Office creates, releases and ensures the implementation of quality management documentations including manuals and SOPs. The IQO also conducts planned internal audit of our laboratories, ensuring compliance to standards and opportunity for continual improvement.

Booking and Request Process for HPLC Analysis

We have streamlined our booking and request process to ensure seamless access to our advanced HPLC analysis services for plant fingerprinting, pharmacokinetics, and related studies. Whether you are a researcher, scientist, or industry professional, we are committed to providing you with accurate and timely results to support your projects.

Requesting Laboratory Examination /Booking Process

Request Forms:

Requests for laboratory examination may be written on the customer’s own request form or on Department of Clinical Pathology laboratory examination request forms. For our examination request form, please phone Department Reception/Administration on +233209196303 +233302940422/ +233302942842.

Kindly e-mail completed examination request form to Department Administration (contact Administrator Angella Asantewaa) at aasantewaa@noguchi.ug.edu.gh. For any assistance or further information, please contact Department Administration on +233209196303 +233302940422/ +233302942842

  • Upon receipt of a completed examination request form, an invoice will be e-mailed from Department Administration to client or patient.
  • Upon receipt of the invoice, make payment at the NMIMR Accounts Office, located in the Main Research Building, of the Noguchi Memorial Institute for Medical Research. Make All payments into the Department of Clinical Pathology account, NMIMR.
  • Client(s) must submit a copy of the payment receipt to the Department Administration after payment and submit the samples for analysis.

Cost/Price of tests/Examination

For information on cost of the HPLC examinations mentioned, please contact Department Administration on 0209196303.

Specimen Collection

A correctly labelled specimen is essential. Persons collecting specimens must positively identify the patient, and ensure that there are at least two unique identifiers recorded on the specimen:

  • Patient first and surname or Project ID, Sample ID.
  • Date of birth (and/ or medical record number for hospital patients). Material type, drug name. etc.

A correctly labelled specimen should arrive in the laboratory with a completed examination request form that includes the date and time of collection.

Opening Times

  • Services run from Monday-Friday, 9am – 3pm

Terms and conditions:

  • Analysis is done on a first-come-first-served basis.
  • The booking form must be completed in full. Results will be sent via emails.
  • Samples submitted to us must be properly collected and stored. We do not accept responsibility for samples not properly collected and stored.
  • Requests for re-analysis of samples by the client will be treated as a new request and should be paid for as such.
  • For research work, we do not interpret analytical results. The raw data will be provided to the test requester for analysis. Data analysis may be undertaken at additional cost.
  • Any remaining samples should be collected within 2 weeks. Else they will be discarded.

Reporting of results:

Reports of laboratory examination results are delivered through email, prioritizing the confidentiality of data and records.

Contact Us:

For further information, please contact us on +233209196303 +233302940422/ +233302942842