Research Projects

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Key Research Activities

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Implementing Cervical Cancer Screening Among Women Living with HIV in Ghana (I-CERV-GH)

Investigating the role and impact of Nano-sized Extracellular VesiclEs and dRug RESisTance in protozoans (The i-NEVER REST project)

SCHISTOSIMIASIS

Malaria genomics

Pan-Africa Network for Genomic Surveillance

NIINE Research Project

Determining the impact of scaling up mass testing, treatment and tracking on malaria prevalence among children in the Pakro sub district of Ghana

Biomarkers of systemic and placental dysfunction in preeclampsia

The impact of hepatitis B co-infection on T cell responses in virologically suppressed HIV patients on ART in Ghana

Determining the Role of Fc gamma Receptor (FCGR) gene polymorphisms in HIV infection progression and treatment outcomes in Ghanaian Adults

Anti-pathogen and toxicological effects of BEEMAR®- A natural honeybee and enhanced marine plasma product

Corona Virus immune epitope discovery

Comparative assessment of immunological responses to different COVID-19 vaccines

Immunological support for on-going clinical trials at NMIMR

Malaria vaccine antigen discovery

African Pathogen Genomics Initiative (Noguchi Africa CDC/WHO Regional Sequencing Hub): HIV drug resistance profile, SARS-CoV-2 and Bacterial Infections in Persons Living with HIV

Gamma delta T cells and naturally acquired immunity to malaria in neonates

Targeted Next Generation Sequencing as a tool for large-scale early diagnosis of inborn errors of metabolism in Ghana

Functional Immuno-genetic Correlates of Immunity to Malaria

Molecular surveillance of glucose-6-phosphate dehydrogenase (G6PD) deficiency and Plasmodium ovale in Ghana

Assessing the effectiveness and cost-effectiveness of Ultra-sensitive RDTs and SD Bioline RDTs in diagnosing asymptomatic parasitaemia in an endemic area in Ghana

Genetic Determinants of Susceptibility to Sars-Cov-2 and Severity of Covid-19 Outcomes Among Ghanaians

Strategies to Develop New Field Blood Sample Diagnostics

Characterization and role analyses of classical human leucocyte antigen in HIV molecular epidemiology, drug resistance and Molecular adaptation in Ghana

Evaluation of the detection of malaria parasite species and anti-malarial resistance in uncomplicated malaria patients using a point of care digital diagnostic 

AQSENS Saliva Project – A Method to Manage and Eradicate Infectious Diseases

Determining whether histidine rich protein gene deletions causing negative HRP2 RDT results among symptomatic patients with confirmed P. falciparum malaria have reached a threshold for change in diagnostic strategy

The role of the mosquito bite on the dynamics and infectiousness-to-mosquito of asymptomatic Plasmodium falciparum carriers in Ghana

Assessing the contribution of children over five years of age to malaria transmission in Northern Ghana.

NTD Research Group

Supporting the Development of a Drug Discovery Hub in Ghana

Genomic Surveillance of enteric viruses

Yaws

Computer-Aided Drug Discovery Program For NTDs Control

Plasmodium falciparum Gametocytogenesis in vitro and in vivo

Woundcare

Skin Health African Research Programme

Surveillance of antimalarial drug resistance in Ghana

Infectious Diseases (Epidemiology, Disease Ecology, Diagnostics)

Drug resistance in malaria infection

Determination of the genetic diversity of histidine rich proteins 2 and 3 (hrp2 and hrp3) gene mutations in Plasmodium falciparum populations in Ghana

The Pan African Vivax and Ovale Network (PAVON): Investigation of the determinants of Plasmodium vivax and P. ovale infections in Ghana: parasites prevalence and host factors.

Mechanisms of antimalaria drug resistance development in Plasmodium falciparum: the role of extracellular vesicles in parasite-parasite communication

Immune mechanisms and host receptor polymorphisms in HIV infection and other infectious diseases

Genetic polymorphisms associated with antimalaria drug resistance in Plasmodium falciparum population in Ghanaian

Vaccine Studies: Clinical Trials for Enteric Virus Vaccines

Measuring the Impact of Rotavirus Vaccines on Paediatric Antibiotic Usage

SafeFish: Improving Tilapia Health to Optimize Yields

The Human Heredity and Health in Africa Kidney Disease Research Network (H3A-KDRN) Genome Laboratory

Newborn Screening For Sickle Cell Disease

Biomonitoring And Control of Environmental Toxicants: Heavy Metals And Mycotoxins

Drug Interactions

Anti-COVID-19 Studies

Antimalarial Studies

Anticancer Studies

Effects of composite foods powder powder intake on nutritional anaemia and growth status of young Ghanaian children under five years of age in Adaklu District, Volta Region, Ghana

The effect of mixed green leafy vegetables powder on vitamin A and anaemia status of Ghanaian school children

Supplementation Trial of KokoPlus for HIV exposed children in Accra

Nudging for Good

Proto-zoonoses

HIV Cure Research Infrastructure Study Group (H-CRIS)

COVID-19 diagnosis

Poliovirus surveillance in Ghana

Molecular Epidemiology of Respiratory Syncytial Viruses in Ghana

National Tuberculosis Control Programme Sputum transport and TB drug-resistant Survey

Early Life Microbiome of Ghanaian Infants

Impact of COVID 19 Control Measures on Health Systems Functioning (UKRI)

Food / Water Safety and One Health

Antimicrobial resistance (AMR)

Diarrhoea Surveillance

Basic Tuberculosis Research

Gut Microbiome

One Health Research on Tuberculosis

Epidemiology and Transmission

COVID 19 and Co-infections

Pneumonia and Meningitis: Towards Vaccine Development

Tuberculosis Comorbidity

Paediatric Tuberculosis

Trachoma

Point of Care Diagnostic Tool Development

Clinical Buruli Ulcer Diagnosis, Trainings & Interventions

COVID-19 (Sampling and Diagnostics)

Lymphatic Filariasis

Neglected Tropical Diseases (Epidemiology, molecular biology, Drug discovery)

Vector Surveillance and Control

Mosquito Microbiome Interactions

Buruli ulcer (Epidemiology, Transmission, Disease Management)

Ticks and tick-borne diseases

Multi-Target Anti-Malaria Development from Medicinal Plants

Insecticide Resistance

Molecular Epidemiology of Dengue Fever & Chikungunya Viruses

Surveillance for Influenza Viruses

Buruli Ulcer Wound Care

Basic Tuberculosis Research